Enantioselective synthesis of d-α-amino amides from aliphatic aldehydes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc00064e Click here for additional data file. Click here for additional data file.

Organocatalytic, enantioselective synthesis of benzoxaboroles via Wittig/oxa-Michael reaction Cascade of α-formyl boronic acids† †Electronic supplementary information (ESI) available. CCDC 1487136. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04522g Click here for additional data file. Click here for additional data file.

Rh-catalyzed desymmetrization of α-quaternary centers by isomerization-hydroacylation† †Electronic supplementary information (ESI) available: Materials and methods, reaction procedures, characterization data. CCDC 1056687, 1062118. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc01553g Click here for additional data file. Click here for additional data file.

We describe a Rh-catalyzed desymmetrization of all-carbon quaternary centers from α,α-bis(allyl)aldehydes by a cascade featuring isomerization and hydroacylation. This desymmetrization competes with two other novel olefin functionalizations that are triggered by C-H bond activation, including carboacylation and bisacylation. A BIPHEP ligand promotes enantioselective formation of α-vinylcyclopen...

Enantioselective α-amination enabled by a BINAM-derived phase-transfer catalyst† †Electronic supplementary information (ESI) available: Procedures and characterization data. CCDC 1025135. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc02494j Click here for additional data file. Click here for additional data file.

Chiral anion phase-transfer of aryldiazonium cations was utilized to achieve highly enantioselective α-amination of carbonyl compounds. A broad scope of indanone- and benzosuberone-derived substrates was amenable to this strategy. Critical to obtaining high levels of enantioselectivity was the use of BINAM-derived phosphoric acids. The utility of this transformation was demonstrated through fac...

Enantioselective dearomatization of isoquinolines by anion-binding catalysis en route to cyclic α-aminophosphonates† †Electronic supplementary information (ESI) available: Experimental details, characterization and analytical data. CCDC 1476699 (4w). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc02466a Click here for additional data file. Click here for additional data file.

Ligand-enabled Ir-catalyzed intermolecular diastereoselective and enantioselective allylic alkylation of 3-substituted indoles† †Electronic supplementary information (ESI) available. CCDC 1060973. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc01772f Click here for additional data file. Click here for additional data file.